Aleksandra Garifulina

aleksandra.garifulina@univie.ac.at

Supervisor: Steffen Hering, University of Vienna

Co-Supervisor: Margot Ernst, Medical University of Vienna

Details

Start of the project: 15.09.2019

Title of the project:  Modulation of Ligand-Gated Ion Channels by Peptides and Low-Molecular-Weight Compounds

Research topic of the student: The aim of the project is the identification of novel modules of ligand-gated ion channels (such as GABAAR, TRPA1, nAChR and others) in peptide libraries (focus on toxins from spider and snake venoms) and libraries of low-molecular-weight compounds.  The selectivity, mechanism and molecular determinants of the ligand-receptor interaction will be analysed. In continuation of the work of Marco Stadler (former MolTag PhD Student) I currently focus on the functional and pharmacological characterisation of proton receptors formed by ß-subunits of GABAA receptors.


Lab rotation period: "Training in the preparation of GABAA receptor subunits RNA for subsequent usage in electrophysiological experiments"; February 2020

Lab Host: Margot Ernst, Medical University of Vienna


Internship abroad: Functional interaction of KIR2.1 and KCC1/KCC2 channels in health and disease; 01.07.2022 - 29.09.2022

Host lab: Department of Medical Physiology at the University Medical Center Utrecht, The Netherlands.


Aleksandra Garifulina has been elected as Student Representative from 03/2022 to 02/2023.


Link to Publications by Aleksandra Garifulina