Chen Xingyu

Supervisor: Anna Weinzinger
Project: in silico investigations of KIR channel inhibition - binding site investigations and mode of action

Mandatory Courses Completed Successfully
SubjectECTS pointsDate
MolTag Journal Club - Medical University of Vienna101/2017
TS Visualization and use of PDB data, MedUni Vienna104/2017
Technical and epistemological challenges in protein-ligand complex crystal structure models 110/2017
Cardiac safety pharmacology212/2017
MolTag Journal Club - Recent Trends in (Bio)Organic Chemistry, TU Vienna...01/2018

Conference Talks
In silico investigations of Kir6 channel inhibition - binding site investigations and mode of actionAnnual CantuTreat Consortium Meeting 2017, St. Louis, US06/2017

Conference Poster Presentations
Computational Investigations of KATP Channel Pore BlockersMolTag Science Day, Vienna, Austria11/2016
Computational Investigations of KATP Channel Pore BlockersBiophysical Society Annual Meeting, New Orleans, US and MolTag Science Day, 11/201602/2017
Computational Investigations of Rosiglitazone Binding to KATP Channels DATA BLITZ and POSTER at FEBS/EMBO lecture course on Ion Channels and Transporters, Erice, Italy05/2017

Lab Rotations Completed Successfully
HostHost institutionSubjectDate of completion
Thierry LangerUniversity of ViennaDynamic pharmacophore models based on rosiglitazone binding to Kir6.1 channel10/2017

Courses and Enabling Skills Seminars
Gromacs Workshop; Max Planck Institute for Biophysical Chemistry, Gottingen, GER 05/2016
Presentation Techniques12/2016
Visualization and use of PDB data, MedUni Vienna 06/2017
Training in interpersonal communication skills & conflict management in the workplace09/2017
Workshop "Career Paths for Natural Scientists", Univ. of Vienna01/2018
Writing scientific publications in peer-reviewed journals04/2018
German language course (A1.1)05/2018
Publication Fraud and how to recognize and deal with it; University of Vienna06/2018

Publications in Peer Reviewed Journals
Conserved functional consequences of disease-associated mutations in the slide-helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel.J Biol Chem. 2017 Aug 23. pii: jbc.M117.804971. doi: 10.1074/jbc.M117.80497108/2017