Marco Niello

Supervisor: Harald Sitte
Project: Swapping the 4-methcathinones selectivity in human dopamine and serotonin transporter

Mandatory Courses Completed Successfully
SubjectECTS pointsDate
Intellectual property rights and project management105/2016
Methods of life sciences206/2016
Ion channels and transporters as drug Targets, Univ. of Vienna206/2016
MolTag Journal Club, Medical University of Vienna101/2017
MolTag Journal Club - Recent Trends in (Bio)Organic Chemistry, TU Vienna...02/2018

Conference Talks
Short talk selected from poster Abstract ("Para-Substituted Methcathinones as Selective and Unselective Inhibitors of Human Dopamine and Serotonin Transporter")Gordon Research Conference 2018, "Membrane Transport Proteins", Sunday River, Newry, MA, USA06/2018

Conference Poster Presentations
Swapping the 4-methcathinones selectivity in human dopamine and serotonin transporterDopamine 2016, Vienna09/2016
Swapping the 4-methcathinones selectivity in human dopamine and serotonin transporterAPHAR, Vienna09/2016
In vitro investigation of alpha-Pyrrolidinopentiophenone enantioselectivityMolTag Science Day, Vienna/AT11/2016
In vitro and in vivo characterization of 1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one (alpha-PVP) enantiomersMonitoring Molecules in Neuroscience 2018, Oxford03/2018

Lab Rotations Completed Successfully
HostHost institutionSubjectDate of completion
Gerhard EckerPharmacoinformatics Research Group, University of ViennaDefinition of docking process and guiding the further experimental approach02/2016

Internships Completed Successfully
HostHost institutionSubjectDate of completion
Roger L. Redondo, Phd, Lab HeadNeuroscience Lab, Roche, Basel (CH)Investigation of substrate selectivity between dopamine and serotonin transporter in anaesthetized and freely moving animals.12/2017

Courses and Enabling Skills Seminars
Signal transduction and Tumorigenesis - Applied Experimental Pharmacology06/2016
Writing scientific publications in peer-reviewed journals04/2018

Publications in Peer Reviewed Journals
Are reprogrammed cells a useful tool for studying dopamine dysfunction in psychotic disorders? A review of the current evidence.European Journal of Neuroscience09/2016
Pronounced Hyperactivity, Cognitive Dysfunctions, and BDNF Dysregulation in Dopamine Transporter Knock-out RatsJ Neurosci. 2018 Feb 21;38(8):1959-1972. doi: 10.1523/JNEUROSCI.1931-17.2018. Epub 2018 Jan 18.02/2018
Neuropharmacology of Synthetic Cathinones.Handbook of Experimental Pharmacology, pp 1-30, 11/2018, doi: 10.1007/164_2018_178 11/2018

TitleFunding organisationDate
Roche Internship for Scientific Exchange (RISE), 12 monthsRoche, Switzerland 10/2016
Award: Best Short Talk PresentationGordon Research Conference "Membrane Transport Proteins"06/2018