Kumaresan Jayaraman

Supervisor: Harald Sitte
Project: Oligomerization of human dopamine transporter (hDAT)


Conference Talks
Subject/TitleConference/PlaceDate
A step towards understanding the energetics of monoamine transporters: lessons learned from a bacterial leucine transporter21st Scientific APHAR Symposium, Graz, Austria09/2015


Conference Poster Presentations
Subject/TitleConference/PlaceDate
Conformational studies of the transmembrane helix 1A in the leucine transporter (LeuT)19th Scientific APHAR Symposium, Vienna, Austria09/2013
Towards developing the full energy profile of substrate transport by the leucine transporter (LeuT) using steered molecular dynamics simulationsPhD Symposium of the Young Scientist Association, Medical University of Vienna06/2014
Toward developing the full energy profile of substrate transport of the leucine transporter (LeuT) using steered molecular dynamics simulations20th Scientific APHAR Symposium, Innsbruck, Austria09/2014
Oligomerization of the Human Dopamine Transporter (hDAT)12th PhD Symposium of the Young Scientist Association, Medical University of Vienna06/2016
Oligomerization of the Human Dopamine Transporter (hDAT)22nd Scientific APHAR Symposium, Vienna, Austria09/2016
Oligomerization of the Human Dopamine Transporter (hDAT)9th SFB Symposium, Vienna, Austria09/2016
Oligomerization of the Human Dopamine Transporter (hDAT)13th PhD Symposium of the Young Scientist Association, Medical University of Vienna06/2017
Conformations and oligomer interfaces of Human Dopamine Transporter (hDAT)23rd Scientific APHAR Symposium, Innsbruck, Austria09/2017


Publications in Peer Reviewed Journals
TitleJournal/VolumeDate
Identifying forces that stabilize the oligomeric state of bacterial homologs of neurotransmitter transportersBMC Pharmacol Toxicol. 2012; 13(Suppl 1): A59. 09/2012
Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.Biochemistry. 2014 Aug 26;53(33):5444-60. 08/2014
Transporters in Motion: Combining Computational Approaches and LRET-MeasurementsBiophysical Journal 108(2):199a ?·DOI: 10.1016/j.bpj.2014.11.110101/2015
The Environment Modulates the Conformation of Transmembrane Helix 1A in the Leucine Transporter (LEUT)Biophysical Journal, Volume 108, Issue 2, Supplement 1, p461a?€“462a,01/2015
The Environment Shapes the Inner Vestibule of LeuT.PLoS Comput Biol. 2016 Nov 11;12(11):e1005197.11/2016
Oligomerization of Human Dopamine Transporter (hDAT)Biophysical Journal, Volume 112, Issue 3, Supplement 1, p127a, 02/2017
Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domainunder Review in Biophysical Journal10/2017


Awards/Scholarships
TitleFunding organisationDate
Travel GrantOeGMBT - Austrian Association of Molecular Life Sciences and Biotechnology09/2014
Travel GrantEuropean Biophysical Societies Assocations (EBSA)07/2015
Travel GrantAustrian Pharmacological Society, 2012, 2014, 2015, 201709/2017