Stefanie Kickinger

Supervisor: Ecker Gerhard
Project: GABA transporter selectivity profiling


Mandatory Courses Completed Successfully
SubjectECTS pointsDate
SE Ion channels and transporters as drug targets206/2016
PR Pharmacoinformatics Practical Course106/2016
VO Pharmacoinformatics106/2016
PR Praktikum aus Computational Drug Design608/2016
MolTag Journal Club, Medical Unviersity of Vienna101/2017
TS Visualization and use of PDB data, MedUni Vienna104/2017


Conference Talks
Subject/TitleConference/PlaceDate
Exploring a new allosteric binding pocket in the GABA transporter hBGT111th European Workshop in Drug Design (EWDD), University of Siena05/2017


Conference Poster Presentations
Subject/TitleConference/PlaceDate
Exploring the structure activity-relationship of novel non-competitive hBGT1 inhibitorseCheminfo Workshop, Milano07/2016
Molecular docking of novel non-competitive hBGT1 inhibitors to explore their structure-activity relationshipEFMC-ISMC 2016, Manchester08/2016
Exploring a new allosteric binding pocket in the GABA Transporter hBGT1MolTag Science Day, Vienna, AT11/2016
Inhibition of GABA transporters as promising drug target for treating epilepsyAnnual Conference of the Austrian Pharmacy Chamber, Schladming03/2017
Identifying the molecular determinants of inhibitors for the subtype-selectivity of the GABA transporter hBGT1Biomedical Transporter Conference, Lausanne08/2017


Lab Rotations Completed Successfully
HostHost institutionSubjectDate of completion
Ass. Prof. Priv.-Doz. Dr. Margot Ernst, Margot Ernst, PhDMedical University of Vienna, Center for Brain ResearchHomology Modeling06/2016


Courses and Enabling Skills Seminars
SubjectDate
Expose and Outline Writing09/2016
Introduction to R11/2016
BioSolveIT Workshop (Introduction to SeeSAR a software tool for structure-based design)05/2017
PRACE Spring School, KTH Royal Institute of Technology in Stockholm, PDC Center for High Performance Computering (Molecular Dynamics simulation training in VMD, GROMACs and CHARMM)05/2017
Introduction to Inkscape (hands-on training for a vector graphics program)05/2017
"Basisqualifizierung fuer Erstlehrende - MINT-Faecher" (Teaching training)06/2017


Publications in Peer Reviewed Journals
TitleJournal/VolumeDate
Damgaard M., Haugaard A.S., Kickinger S., Al-Khawaja A., Lie M.E., Ecker G.F., Clausen R.C., Frolund B. Development of non-GAT1 selective inhibitors; challenges and achievements. Advances in Neurobiology, volume 16 08/2017
Anas Al-Khawaja, Jorgensen L., Kickinger S., Vogensen S.B., Skovgaard-Petersen J., Rosenthal E., Borkar N., Loeffler R., Madsen K.K., Braeuner-Osborne H., Schousboe A., Ecker G.F., Wellendorph P., and Clausen R.P. Structure-activity relationship, pharmacological characterization and molecular modeling of selective non-competitive inhibitors of the betaine/gamma-aminobutyric acid transporter 1(BGT1). In revisionJ. Med. Chem. (2017)09/2017
Anas Al-Khawaja, Anne Staehr Haugaard, Stefanie Kickinger, Rebekka Loeffler, Maria Damgaard, Gerhard F. Ecker, Bente Frolund, and Petrine Wellendorph. Structure-activity relationship and molecular determinants for the subtype-selectivity of betaine/GABA transporter 1 (BGT1) inhibitors. SubmittedJ. Med. Chem (2017)09/2017


Awards/Scholarships
TitleFunding organisationDate
Poster award for "Inhibition of GABA transporters as promising drug target for treating epilepsy"Austrian Pharmacy Chamber03/2017
"Best Oral Communication Award" Among Young Researchers Session Drug Design Workshop EWWD, Siena05/2017