Dr. Anna Weinzinger

E-mail: anna.stary@univie.ac.at

Group page: http://www.univie.ac.at/ptox/page.php?p=modelling

Address:
University of Vienna
Dept. of Pharmacology and Toxicology
Althanstrasse 14
1090 Vienna
Austria


Researcher's Profile
Research interests:

In silico membrane protein structure prediction & validation
Molecular dynamics simulations of ion channels
Drug – Receptor analyses (Docking, MD simulations, free energy calculations)

Anna Weinzinger received her doctoral degree in Natural Sciences from the University of Vienna, Austria in October 2007. In 2008 she joined the Max Planck Institute of Biophysical Chemistry, in Goettingen, Germany, as postdoc. In 2009 she returned to Vienna, where she habilitated in Pharmacoinformatics in 2015. In 2012 she was awarded the Gertrud Pleskot Award. Currently she holds a tenure track position in Computational and Structural Biology at the Department of Pharmacology and Toxicology, at the University of Vienna, Austria. Her current research interests include structure and dynamics of voltage and ligand gated ion channels, molecular mechanisms of ion channel disease and modulation of ion channels by small molecules. She is teaching molecular modeling and pharmacokinetics. Dr. Weinzinger is an associate editor for the journal frontiers in cardiac electrophysiology.

Career highlights:

  • Since 01/2016 Tenure Track Contract at the University of Vienna
  • 10.2015 Habilitation in Pharmacoinformatics
  • Since 04/2014 Group Leader, Molecular Modeling Group, Department of Pharmacology and Toxicology, University of Vienna
  • 2008 – 2009 Post-Doctoral Research, Max-Planck Institute for Biophysical Chemistry (Germany). Advisor: Prof. Dr. Bert de Groot
  • 10.2007 Doctoral Thesis with highest honors

Selected Grants and Awards:

2016 Kardinal Innitzer Award for Habilitation
ERANET e-rare2 (2015-2017), FWF
Johanna Mahlke geb. Obermann Stiftung (2014-2015)
2012 Pleskot Award, Faculty of Life Sciences, University of Vienna

Ongoing MolTag Research projects as Supervisor:
Harald BERNSTEINER: Investigating inherited mutations in KATP channels causing Cantu disease
Xingyu Chen: In silico investigations of KIR channel inhibition - binding site investigations and mode of action

Ongoing MolTag Research projects as Co-Supervisor:
Stanislav ANDRANOVITS: Probing the role of voltage sensors in calcium channel inactivation and inhibition by antagonists
Eva HELLSBERG: Selectivity Profiling of the human Monoamine Transporters: Uptake Inhibitors vs. Substrate Releasers

Completed MolTag Research projects as Supervisor:

Ke SONG: Computer Simulations on Voltage Gated Calcium and Sodium Channels; finished 04/2015
Tobias LINDER: Pore gating of potassium channels and dissociation of hERG channel inhibitors , finished 12/2014
Eva-Maria ZANGERL-PLESSL: Gating investigations on inward rectifier potassium channels, finished June 2016

Co-Supervisor:

Roshan PUTHENKALAM: Understanding subtype selective allosteric modulation of GABA A receptors; finished 02/2016
Priyanka SAXENA: Probing the architecture of hERG potassium channel with drugs; finished 11/2015
Peter LUKACS: Exploring an External Access Pathway for Local Anesthetics in the Voltage-Gated Na+ Channel; finished 02/2016